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Andreas Brodehl Selected Research

Proteins (Proteins, Gene)

1/2021The Combined Human Genotype of Truncating TTN and RBM20 Mutations Is Associated with Severe and Early Onset of Dilated Cardiomyopathy.
11/2020Distinct Myocardial Transcriptomic Profiles of Cardiomyopathies Stratified by the Mutant Genes.
11/2020Cardiomyopathy-associated mutations in the RS domain affect nuclear localization of RBM20.
1/2019Noncompaction cardiomyopathy is caused by a novel in-frame desmin (DES) deletion mutation within the 1A coiled-coil rod segment leading to a severe filament assembly defect.
8/2018Molecular insights into cardiomyopathies associated with desmin (DES) mutations.
3/2016Mutations in FLNC are Associated with Familial Restrictive Cardiomyopathy.
5/2012Dual color photoactivation localization microscopy of cardiomyopathy-associated desmin mutants.

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Andreas Brodehl Research Topics

Disease

17Cardiomyopathies (Cardiomyopathy)
06/2022 - 05/2012
5Restrictive Cardiomyopathy
04/2022 - 03/2016
4Muscular Diseases (Myopathy)
01/2019 - 05/2012
3Heart Failure
06/2022 - 12/2010
2Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
06/2022 - 01/2021
2Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2021 - 12/2013
2Atrioventricular Block
01/2021 - 01/2018
2Arrhythmogenic Right Ventricular Dysplasia (Arrhythmogenic Right Ventricular Cardiomyopathy)
05/2012 - 12/2010
1Muscular Dystrophies (Muscular Dystrophy)
06/2022
1Fibrosis (Cirrhosis)
01/2021
1Left Ventricular Dysfunction
01/2021
1Mitochondrial Diseases (Mitochondrial Disease)
03/2020

Drug/Important Bio-Agent (IBA)

13DesminIBA
10/2021 - 12/2010
7Proteins (Proteins, Gene)FDA Link
01/2021 - 05/2012
2RNA (Ribonucleic Acid)IBA
11/2020 - 10/2018
1Creatine Kinase (Creatine Phosphokinase)IBA
06/2022
1Dystroglycans (Dystroglycan)IBA
06/2022
1RNA Splicing FactorsIBA
01/2021
1Pharmaceutical PreparationsIBA
11/2020
1Succinic Acid (Succinate)IBA
03/2020
1Transcription Factors (Transcription Factor)IBA
09/2019
1integrin-linked kinaseIBA
01/2019
1Membrane Proteins (Integral Membrane Proteins)IBA
10/2018
1FilaminsIBA
12/2017
1Crystallins (Crystallin)IBA
01/2017

Therapy/Procedure

2Heart Transplantation (Grafting, Heart)
04/2022 - 03/2016
1Therapeutics
01/2020